With the continuous exploitation of easy-to-treat gold ores, the resources of easy-to-leaching gold ores that can be directly extracted by cyanidation are increasingly exhausted, and refractory (refractory) gold ores have become an important new resource for gold mines. It is estimated that there are at least 1 One-third of gold production disks are from refractory gold deposits. Therefore, how to effectively and sustainably develop and utilize refractory gold ore has become the most important research topic in gold extraction research. In my country, the proven reserves of refractory gold are more than 700t, and there are problems such as low recovery rate of combined metallurgy and highest gas consumption. one of the problems. For refractory gold ores, it is difficult to obtain a satisfactory recovery rate of gold ore and flotation concentrate by directly treating the gold ore with fluoride, and will consume a large amount of fluoride. In order to solve this problem, there are currently three pretreatment methods. That is, conventional oxidative roasting, hot pressing leaching and bacterial oxidation.